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Severe overdosage may perhaps bring about coma, areflexia, cardiorespiratory melancholy and apnea. The consequences of overdosage could be managed with benzodiazepine antagonist flumazenil.
Keep in mind, preserve this and all other medicines out of your attain of children, in no way share your medicines with others, and use this medication just for the indication prescribed.
Even though it can help Lots of individuals, this medication could occasionally result in dependancy. This possibility could be better For those who have a material use ailment (including overuse of or dependancy to drugs/Liquor).
Midazolam can sluggish or cease your respiratory, especially if you might have just lately applied an opioid medication, alcohol, or other medicines that could slow your respiratory.
Benzodiazepines bind to your benzodiazepine web site on GABA-A receptors, which potentiates the results of GABA by increasing the frequency of chloride channel opening. These receptors are identified in several body tissues including the coronary heart and skeletal muscle mass, Even though generally seem like present within the central nervous method.
Soon When you are treated with midazolam, utilizing other prescription drugs that make you sleepy or sluggish your breathing can result in unsafe Unintended effects or Demise. Check with your doctor before applying opioid medication, a sleeping tablet, a muscle mass relaxer, or medication for anxiousness or seizures.
Individual guidance courses (PAPs) are usually sponsored by pharmaceutical firms and supply cost-totally free or discounted medicines, in addition to copay programs, to people today with lower income or those people who are uninsured/below-insured and fulfill specific criteria.
If you use midazolam throughout pregnancy, your little one may be born with life-threatening withdrawal symptoms, and might require health care procedure for a number of months.
Get unexpected emergency health care enable When you've got indications of an allergic response: hives; tricky respiration; swelling of your respective facial area, lips, tongue, or throat.
Specific features could be printable from a web site while some may possibly check here require registration, finishing a questionnaire, or obtaining a sample from a medical Experienced. Prescription drugs.com Printable Price reduction Card
Midazolam should not be offered to sufferers with serious respiratory insufficiency, significant hepatic insufficiency, myasthenia gravis, snooze apnea syndrome and with acknowledged hypersensitivity to benzodiazepines or to any ingredient of your item
Drug interactions might transform how your medicines operate or raise your danger for really serious Unwanted effects. This doc does not have all probable drug interactions.
Downsides include a high degree of breakthrough seizures—due to the quick fifty percent-lifetime of midazolam—in more than 50% of people taken care of, and also therapy failure in 14–eighteen% of those with refractory status epilepticus. Tolerance develops fast to the anticonvulsant impact, and the dose may should be improved by various occasions to maintain anticonvulsant therapeutic consequences.
Midazolam is injected right into a muscle or into a vein. A healthcare service provider offers you this injection.